Ch’uhu unquy sutiyuq p'anqap pukyu qillqanta qhaway

{{pp-semi-indef}}
{{Infobox disease
| Name           = Common cold
| Image          = Rhinovirus.PNG
| Caption        = A representation of the molecular surface of one variant of human [[rhinovirus]].
| ICD10          = {{ICD10|J|00}}
| ICD9           = {{ICD9|460}}
| DiseasesDB     = 31088
| MedlinePlus    = 000678
| eMedicineSubj  =
| eMedicineTopic =
| eMedicine_mult = {{EMedicine2|med|2339}}
| MeshID         = D003139
}}
<!-- Síntomas causasnin ima -->
Kay '''ch’uhu unquy''' (chantapas kay '''nasofaringitis''', '''rinofaringitis''', utaq '''ch’uhu''') huk chimpachikuq vías respiratorias superiores kaqmanta unquy kaytaq ñawpaqta sinqaman hap’in. Aswan riqsisqa unqunayaq kanku ch’uju, kunka nanay, qhuña chaymanta k’aja ima chaymanta qamchismanta chunka p’unchawtahina qukun, ichaqa wakin kutiqa kimsa simanatahina qukun. Aswan kay 200 virusmanta kay ch’uju unquyta hap’ichikun, ichaqa aswan riqsisqaqa kanku kay rinovirus kaqkuna.

<!—Hark’akuy, diagnóstico chaymanta fisiopatología ima -->
Kay vías respiratorias superiores kaqmanta chimpachikuykunaqa rak’ikunku mayqin kurpu k’uchumanchus hap’ikun chaymanhina. Aswan riqsikuq kutitaqa, kay ch’uju unquyqa sinqaman, kunkaman (faringitis) chaymanta kay senos paranasales (sinusitis) kaqman ima hap’in. Kay unqunayaq qukun kay inmunológica kutichiy kurpumantarayku kay chimpachikuq kaqman manataq aswantachu kay tejido thantakuy kay virus kaqraykuhinachu. Aswan riqsisqa hark’ayqa kan makita mayllakuna, ichapas nikun kay uyapaq máscaras kaqkunata churakuy kusallataq. 

<!-- Hampiynin, epidemiología chanta rikhurimuynin ima -->
Mana hampiy kay ch’uju unquypaq tiyanchu, ichaqa unqunayaqnin hampikunman. Kayqa aswan hap’ikuq runakunapurapi chimpachikuq unquy: machu runaqa iskayta utaq kimsa kutita watapi hap’ichikun, wawataq suqtamanta chunka iskayniyuqkama kutita. Kay unquy chimpakuykunaqa ñawpamantapacha runata qatimun. 

==Unanchaq chaymanta unqunayaq==
Aswan riqsisqa unqunayaq huk ch’uju unquymanta kanku, ch’uju, qhuña sinqa wichq’akuywan chaymanta kunka nanay ima. Wakin kutiqa, aycha nanay, sayk’u, uma nanay chaymanta yarqhay chinkapuy ima kanman.<ref name=E24>Eccles Pg. 24</ref> 40% kaqpi casosmanta kunka nanay tiyan, 50% kaqpi ch’uju tiyan<ref name=CE11/> chaymanta khuskanpi kay casosmanta aycha nanay.<ref name=Eccles2005/> Machu runaqa mana k’ajayuqchu kanku, ichaqa wawakunaqa ari.<ref name=Eccles2005>{{cite journal | author = Eccles R |title = Understanding the symptoms of the common cold and influenza | journal = Lancet Infect Dis | volume = 5 | issue = 11 | pages = 718–25 | year = 2005 | month = November | pmid = 16253889 | doi = 10.1016/S1473-3099(05)70270-X }}</ref> Ch’ujuqa mana ancha sinchichu kay influenza kaqta qatiq kaqman tupachispa.<ref name=Eccles2005/> Kay ch’ujupas chaymanta k’ajapas ima machu runakunapi influenza ñisqata willaptinpas, rich’akuykuna tiyan kay iskay unquykunapi.<ref>Eccles Pg.26</ref> Achkha kay viruskunamanta ch’uju unquyta hap’ichikuq, kay asintomaticas chimpachikuykunata hap’ichillanmantaq.<ref>Eccles Pg. 129</ref><ref>Eccles Pg.50</ref> Llimp’iqa kay llawsamanta utaq qhuñamantaqa ch’uwa, q’illu utaq q’umir kanman chaymanta mana willanchu ima laya viruschus kay chimpakuyta ruwachiq.<ref>Eccles Pg.30</ref>

===Thaskiynin===
Aswan rikukuqpi, ch’uju unquyqa sayk’uywan, chiriwan, achhuykunawan chaymanta uma nanaywan ima qallarin. Chaymanta machkha p’unchaw qhipantaqa qhuña chaymanta ch’uju qallarin.<ref name=E24/> Unqunayaq kaqkunaqa kay ñawpaq 16 phanikunapi rikhurinman <ref>{{cite book|first=editors, Richard A. Helms|title=Textbook of therapeutics : drug and disease management|year=2006|publisher=Lippincott Williams & Wilkins|location=Philadelphia, Pa. [u.a.]|isbn=9780781757348|pages=1882|url=http://books.google.ca/books?id=aVmRWrknaWgC&pg=PA1882|edition=8.}}</ref> chaymanta aswan sinchinman chayan iskaymanta tawa p’unchawmanhina qallarisqanmanta.<ref name=Eccles2005/><ref>{{cite book|last=al.]|first=edited by Helga Rübsamen-Waigmann ... [et|title=Viral Infections and Treatment.|year=2003|publisher=Informa Healthcare|location=Hoboken|isbn=9780824756413|pages=111|url=http://books.google.ca/books?id=AltZnmbIhbwC&pg=PA111}}</ref> Aswan rikukuqpi qamchis p’unchawmanta chunka p’unchawpihina chinkapun, ichaqa kimsa semanata unayllanman.<ref name=Heik2003>{{cite journal | author = Heikkinen T, Järvinen A | title = The common cold | journal = Lancet | volume = 361 | issue = 9351 | pages = 51–9 | year = 2003 | month = January | pmid = 12517470 | doi = 10.1016/S0140-6736(03)12162-9 }}</ref> 35-40% kaqpi kay wawakuna casosmanta, ch’ujuqa aswan chunka p’unchawkunamanta unayllan chaymanta aswan 25 kaqmanta 10% kaqpi.<ref>{{cite journal | author = Goldsobel AB, Chipps BE | title = Cough in the pediatric population | journal = J. Pediatr. | volume = 156 | issue = 3 | pages = 352–358.e1 | year = 2010 | month = March | pmid = 20176183 | doi = 10.1016/j.jpeds.2009.12.004 }}</ref>

==Nanachiq==
===Virus===
[[Image:Coronaviruses 004 lores.jpg|thumb|Kay coronavirus kaqkunaqa huk qutuchasqa virus kanku ancha riqsisqakuna kay ch’uju unquyta hap’ichiqrayku. Huk microscopio electrónico kaqpi qhawakuptinku, huk muyu utaq pilluhinaman rich’akuspa rikukunku.]]
Kay ch’uju unquyqa huk viral chimpakuy kay vías respiratorias superiores kaqmanta. Kay aswan riqsikuq virus hap’ichiq kaqqa kan kay rinovirus kaq (30–80%), huk picornavirus laya kan kay 99 riqsisqa serotipos kaqwan.<ref>{{cite journal | author = Palmenberg AC, Spiro D, Kuzmickas R, Wang S, Djikeng A, Rathe JA, Fraser-Liggett CM, Liggett SB | title = Sequencing and Analyses of All Known Human Rhinovirus Genomes Reveals Structure and Evolution | journal = Science | volume = 324 |issue = 5923 | pages = 55–9 | year = 2009 | pmid = 19213880 | doi = 10.1126/science.1165557 }}</ref><ref>Eccles Pg.77</ref> Wakkunaq tiyapunku: coronavirus (10–15%), influenza (5–15%),<ref name=Eccles2005/> parainfluenza, virus sincitial respiratorio runamanta, adenovirus, enterovirus, chaymanta metapneumovirus.<ref name="NIAID2006">{{cite web | title = Common Cold | publisher = [[National Institute of Allergy and Infectious Diseases]] | date = 27 November 2006 | url =http://www3.niaid.nih.gov/healthscience/healthtopics/colds/ | accessdate = 11 June 2007}}</ref> Achkha kutiqa aswan huk virusmanta tiyan.<ref>Eccles Pg.107</ref> Tukuyta yupaspa, aswan kay 200 laya virales ukhina ch’uju unquykunamanta tiyan.<ref name=Eccles2005/>

===Chimpachikuy===
Kay ch’uju unquymanta virusqa chimpakun kay wayrapi yakumanta (aerosol), chiqan tinkunakuna kay chimpachisqa sinqamanta yakukunawan utaq fómites kaqwan ima (chimpachisqa imakuna).<ref name=CE11/><ref name=Cold197>{{cite book|last=editors|first=Ronald Eccles, Olaf Weber,|title=Common cold|year=2009|publisher=Birkhäuser|location=Basel|isbn=978-3-7643-9894-1|pages=197|url=http://books.google.ca/books?id=rRIdiGE42IEC&pg=PA197|edition=Online-Ausg.}}</ref> Mana yachakunraqchu mayqinchus kay ñankunamanta aswan chaninniyuq.<ref name=E211>Eccles Pg.211</ref> Kay viruskunaqa kawsankuman unayta wayrapi chaymanta runakunataq makinkupi, ñawinkupi chaymanta sinqankupi ima apankuman, ahinata imaynatachus kay chimpachiy rinhina.<ref name=Cold197/> Kay chimpachiyqa aswan rikukun kay guarderías kaqpi chaymanta yachaywasikunapi ima, mayqinpichus wawas pikunachus mana unqunapaq sistemas kaqninku mana allin hatunllasqaschu chaymanta pisi llimphus kanku khuska kachkankurayku.<ref name=Text2007/> Kay chimpachikuykunaqa wasiman apakunku chaymanta wak yawarmasikunamantaq chimpachikun.<ref name=Text2007>{{cite book|last=al.]|first=edited by Arie J. Zuckerman ... [et|title=Principles and practice of clinical virology|year=2007|publisher=Wiley|location=Hoboken, N.J.|isbn=978-0-470-51799-4|pages=496|url=http://books.google.ca/books?id=OgbcUWpUCXsC&pg=PA496|edition=6th}}</ref> Mana yachakunku kay wayra hallich’asqa vuelos comerciales nisqakunapi huk chimpakuy ñan kachkanta.<ref name=Cold197/> Ichaqa, pikunachus qayllaman chukunku chaykuna aswan qaylla chimpachikunamanta kanku.<ref name=E211/> Kay virus ruwachisqas kay rinovirus kaqrayku aswan chimpachiq kanku kay ñawpa kimsa p’unchawkuna unqunayaqmanta, chantataq aswan pisi chimpachikuqkunaman tukupunku.<ref name="contagiousness">{{cite journal | author = Gwaltney JM Jr, Halstead SB | title = Contagiousness of the common cold| journal = Journal of the American Medical Association | volume = 278 | issue = 3 | pages =  256| year = 1997 | month = July | pmid =  | doi = 10.1001/jama.1997.03550030096050 }}</ref>

===Clima===
Ñawpa ñiykunaqa ñin hukqa ch’uju unquyta hap’inman kay chiri pachapi unayta kaqrayku, parahina utaq invernal pachahina chaymanta chayhinata karqa imaynatachus unquy sutinta hap’irqa.<ref>{{cite news |author=Zuger, Abigail |title='You'll Catch Your Death!' An Old Wives' Tale? Well.. |newspaper=[[The New York Times]] |date=4 March 2003|url=http://www.nytimes.com/2003/03/04/science/you-ll-catch-your-death-an-old-wives-tale-well.html}}</ref> Kay kurpumanta chirillay ruwayninqa huk riesgo factorhina ch’aqwakuman apan kay ch’uju unquypaq.<ref name="Mourtzoukou">{{cite journal | author = Mourtzoukou EG, Falagas ME | title = Exposure to cold and respiratory tract infections | journal = The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease | volume = 11 | issue = 9 | pages = 938–43 | year = 2007 | month = September | pmid = 17705968 | doi =  }}</ref> Wakinkuna kay ch’uju unquyta hap’ichiq viruskunamanta estacionales kanku chaymanta aswanta hap’ikun kay chiri utaq huq’u pachapi.<ref>Eccles Pg.79</ref> Wakinkuna ñinku kayqa kan imaraykuchus wichq’asqa wasikunapi anchata kankurayku chaymanta wak runakuna qayllanpirayku; <ref name="EcclesPg">Eccles Pg.80</ref> aswanta kay wawakuna yachaywasiman kutinku chaykunapi.<ref name=Text2007/>Ichaqa, kay sistema respiratorio kaqpi tikraykunarayku kanman mayqinchus aswan manchhichiyta qukun.<ref name="EcclesPg" /> Kay huq’u pacha achkhallachinman kay viral chimpachiyta imaraykuchus ch’aki wayra yanapan kay huch’uy partículas virales aswan karuman chayanankupaq chaymanta aswan unayta wayrapi kanankupaq. <ref>Eccles Pg. 157</ref>

===Wakkuna===
Kay achkha runa unquymanta hark’akunaqa, ruwasqa huk ñawpa tinkunarayku kay ch’uju unquy viruskunaman, huk sinchi llamk’ayniyuq kay viral mirayninmanta hark’ayninpi, imaynatachus rikuchikun kay aswan wayna ayllukunapihina mayqinkunachus achkha tasasniyuq kay respiratorias chimpachikuykunamanta.<ref name=E78/> Wak riesgo factorqa kan huk pisi mana unqunapaq kay.<ref name=E78/><ref>Eccles Pg.166</ref> Kayman k’askakun kay mana puñuy atikuy chaymanta ancha tuyu kay ima aswan riesgoyuq kay chimpachiyta llamk’achinapaq kay tinkuna qhipanta huk rinovirus kaqman. Ñikun efectosninman k’askasqa kachkanta kay mana unqunapaq sistema kaqpi.<ref>{{cite journal | author = Cohen S, Doyle WJ, Alper CM, Janicki-Deverts D, Turner RB | title = Sleep habits and susceptibility to the common cold | journal = Arch. Intern. Med. | volume = 169 | issue = 1 | pages = 62–7 | year = 2009 | month = January | pmid = 19139325 | pmc = 2629403 | doi = 10.1001/archinternmed.2008.505 }}</ref><ref>Eccles Pg.160–165</ref>

==Fisiopatología==
[[Image:Illu conducting passages.svg|thumb|Kay ch’uju unquyqa huk unquy kay vías respiratorias superiores kaqmanta]]
Ñikun kay ch’uju unquy unqunayaq kaqninqa aswan k’askasqa kachkanku kay inmunológica kutichiywan kay virusman.<ref name=E112>Eccles Pg. 112</ref> Kay mecanismo kay mana unqunapaq kutichiymantaqa sumaq riqsisqa sapa virusmanta. Ahinata, kay rinovirus kaqkunaqa chiqan tinkuywan chimpachikun; kay runa ICAM-1 receptoresman k’askakunku huk mana riqsisqakuna mecanismos kaqninta mayqinkunachus kay punkiymanta mediadores ruwaqkunata kacharinku.<ref name=E112/> Kay mediadores unqunayaqta ruwachinku.<ref name=E112/> Aswan rikukuqpi mana waqllinkuchu epitelio nasal kaqta.<ref name=Eccles2005/> Wakhinamanta, kay sincitial respiratorio (VSR) virusqa anchata chimpachikun chiqan tinkuywan chaymanta wayrapi yaku kaqninta. Chaymanta sinqapitaq kunkapitaq karinku manaraq vías respiratorias inferiores kaqman chayaptin.<ref name=E116>Eccles Pg.116</ref> Kay VSR kaqqa ari kay epitelial waqlliyta ruwan.<ref name=E116/> Kay parainfluenza aswan rikukuqpi sinqa, kunka chaymanta bronquios ima punkiyta qukun.<ref name=E122>Eccles Pg.122</ref> Huch’uy wawakunapiqa, tunqurita waqlliptin, kay crup unqunayaqninta qunman imaraykuchus kay vías respiratorias huch’uy kayninrayku.<ref name=E122/>

==Diagnóstico==
Kay ukhinallachiy kay virales chimpachikuy vías respiratorias kaqpuramanta unqunayaq maypichus kanman ahinaman llamk’an. Kay ch’uju unquyqa aswanta sinqaman waqllin, kay faringitis kaqqa kunkaman, chaymanta bronquitis kaqqa surk’anman.<ref name=CE11/> Ichaqa, achkha kikin unqunayaqniyuq kanman chaymanta achkha partes waqllisqas rikukunkuman.<ref name=CE11/> Kay ch’uju unquyqa aswan rikukuqpi rinitis kaqhina utaq sinqa punkiy kaqhina riqsikun, huk tikrakuq ñiqiwan kay kunka punkiymanta.<ref name=E51>Eccles Pg. 51–52</ref> Ancha rikukuq unqusqaqa sapan qhawakun.<ref name=Eccles2005/> Aswan rikukuqpiqa mana karunchakunchu kay agente viral kaqqa<ref name=E51/> chaymanta mana riqsiy atikunchu ima laya viruschus kasqanta kay unqunayaqpi umachakuspa.<ref name=Eccles2005/>

==Hark’akuynin== 
Kay físicas hark’akuykunaqa kay ch’uju unquy virus mirakuymanta hark’akunapaqqa, sumaq kaq hark’akuykunalla kankuman hark’akunapaq.<ref name=E209>Eccles Pg.209</ref> Kaytaq maki mayllakuykunawan chaymanta barbijos churakuywan ima kan. Kay hampiwasi kitipi, qara makikunata chaymanta batata ima churakunku.<ref name=E209/> Mana allinchu ruwanaqa huk cuarentena kaqtaqa imaraykuchus unquyqa ancha riqsisqa chaymanta unqunayaq pisi aqllasqas kanku. Vacunacionqa ancha sasa imaraykuchus ancha achkha involucrasqa virus kan chaymanta usqhaytapacha wiñanku.<ref name=E209/> kay huk allin vacunamanta paqarichiyqa kan, ahinataqa, pisi atikuq.<ref>{{cite journal | author = Lawrence DM | title = Gene studies shed light on rhinovirus diversity | journal = Lancet Infect Dis | volume = 9 | issue = 5 | pages =  278| year = 2009 |month = May | pmid =  | doi = 10.1016/S1473-3099(09)70123-9 }}</ref>

Sapa kuti maki mayllakuyqa allinsina kanman kay ch’uju unquy virus chimpachiy pisillananpaq, aswanta wawakunapurapi.<ref name=CochP11>{{cite journal | author = Jefferson T, Del Mar CB, Dooley L, Ferroni E, Al-Ansary LA, Bawazeer GA, van Driel ML, Nair S, Jones MA, Thorning S, Conly JM | title = Physical interventions to interrupt or reduce the spread of respiratory viruses | journal = Cochrane Database of Systematic Reviews | volume =  | issue = 7 |pages =  CD006207| year = 2011 | month = July | pmid = 21735402 | doi = 10.1002/14651858.CD006207.pub4 | editor1-last = Jefferson | editor1-first = Tom }}</ref> Mana yachakunchu sichus antivirales kaqkunata chaymanta antibacteriales kaqkunata yapayqa kay maki mayllakuyman aswan kusa kasqanta.<ref name=CochP11/> Kay barbijos churakuyqa unqusqa runakunawan tinkuypiqa allin kanman kasqa; ichaqa, mana achkha rikukuq kanchu runakunamanta karunchasqa kachinapaq.<ref name=CochP11/> Kay suplementos zinc kaqwan hampikuyqa allin kanman ch’uju unquy casosta pisillachinapaq.<ref name=Zinc11>{{cite journal | author = Singh M, Das RR | title = Zinc for the common cold | journal = Cochrane Database of Systematic Reviews | volume =  | issue = 2 | pages =  CD001364| year = 2011 | month = February |pmid = 21328251 | doi = 10.1002/14651858.CD001364.pub3 | editor1-last = Singh | editor1-first = Meenu }}</ref> Kay sapa kuti jampi upyanaqa kay vitamina C kaqwan suplementosmanta mana ch’uju unquy riesgonta utaq sinchiyninta pisillachinchu.<ref name="Hemilä2010"/>

==Hampikuynin==
[[Image:Pneumonia strikes like a man eating shark.jpg|thumb|Poster mayqinchus runakunata hampiq runanta tapunanpaq sunquchan kay ch’uju unquy hampikuyninpaq]]
Kunankamaqa mana hampikuna utaq qhura hampikuna kanchu mayqinkunamantachus allin hampiynin sumaq evidenciasniyuq kasqanta kay chimpakuymanta unayllanninta huch’uyllachinapaq.<ref>{{cite web| title = Common Cold: Treatments and Drugs| publisher = Mayo Clinic| url =http://www.mayoclinic.com/health/common-cold/DS00056/DSECTION=treatments-and-drugs| accessdate = 9 January 2010}}</ref>, Ahinatataq, hampikuyninqa unqunayaq kaqllata chinkachinqa.<ref name=AFP07/> Sumaqta samarina, yakusta upyana, huq’u ukhunchik kananpaq chaymanta q’uñi millu yakuwan kunkata qhulluqachiyta ruwana ima allin ruwaykuna hampikunapaq kan.<ref name="NIAID2006"/> Aswan achkha kusallayninkunaqa kay hampikuyninmanta yapakunku kay placebo efectoman.<ref>Eccles Pg.261</ref>

===Unqunayaq===
Kay hampikuyninkunaqa mayqinkunachus unqunayaq kaqkunata sanillachiy yanapaq analgésicos kaqkunawan chaymanta simples antipiréticos kay ibuprofeno kaqhina kaqkunawan ima hamun<ref>{{cite journal | author = Kim SY, Chang YJ, Cho HM, Hwang YW, Moon YS | title = Non-steroidal anti-inflammatory drugs for the common cold | journal = Cochrane Database Syst Rev | volume =  | issue = 3 | pages =  CD006362| year = 2009 | pmid = 19588387 | doi = 10.1002/14651858.CD006362.pub2 | editor1-last = Kim | editor1-first = Soo Young }}</ref> chaymanta kay paracetamol kaqwan ima.<ref>{{cite journal | author = Eccles R | title = Efficacy and safety of over-the-counter analgesics in the treatment of common cold and flu | journal = Journal of Clinical Pharmacy and Therapeutics | volume = 31 | issue = 4 | pages = 309–319 | year = 2006 | pmid = 16882099 | doi = 10.1111/j.1365-2710.2006.00754.x }}</ref> Evidencias kaqqa mana rikuchinchu kay ch’ujupaq hampikuna aswan kusa kasqankuta kay chhilli analgésicos kaqkunamanta<ref>{{cite journal | author = Smith SM, Schroeder K, Fahey T | title = Over-the-counter (OTC) medications for acute cough in children and adults in ambulatory settings | journal = Cochrane Database Syst Rev |volume =  | issue = 1 | pages =  CD001831| year = 2008 | pmid = 18253996 | doi = 10.1002/14651858.CD001831.pub3 |editor1-last = Smith | editor1-first = Susan M }}</ref> manataq wawakunapi qukunan munakunchu kay mana evidencia kaqtinrayku mayqinchus kusa kayninta utaq waqlliypaq potencialninta rikuchiq.<ref name=CFP09>{{cite journal | author = Shefrin AE, Goldman RD | title = Use of over-the-counter cough and cold medications in children | journal = Can Fam Physician |volume = 55 | issue = 11 | pages = 1081–3 | year = 2009 | month = November | pmid = 19910592 | pmc = 2776795 | doi =  |url = http://www.cfp.ca/content/55/11/1081.full.pdf }}</ref><ref>{{cite journal | author = Vassilev ZP, Kabadi S, Villa R | title = Safety and efficacy of over-the-counter cough and cold medicines for use in children | journal = Expert opinion on drug safety | volume = 9 | issue = 2 | pages = 233–42 | year = 2010 | month = Mar | pmid = 20001764 | doi = 10.1517/14740330903496410 }}</ref> 2009 kaqpi, Canada ch’uju unquypaq chaymanta ch’ujupaq hampikunata pillamanpas ranqhay churakuyta hark'arqa suyk’a wawakunapi suqta watamanta, imaraykuchus mana kusa hampiynin kaqmanta rikukuq kasqanrayku chaymanta kay phuti riesgostachus ruwanrayku ima.<ref name=CFP09/> Mana allin kamachiynin kay dextrometorfano kaqmanta (huk pillamanpas ranqhakuq ch’ujupaq hampi) hark’ana kaqninman aparqa achkha suyukunapi.<ref>Eccles Pg. 246</ref>

Machu runakunapi, qhuña unqunayaq antihistamínicos primera generación kaqmanta kaqwan pisillachikunman; ichaqa mana allin rikukuqniyuqman t’inkikun kay somnolencia kaqhina.<ref name=AFP07/> Wak sinqa kicharichiqkuna kay pseudoefedrina kaqhina allinllataq kanku kay ayllupi.<ref>{{cite journal | author = Taverner D, Latte GJ | title = Nasal decongestants for the common cold | journal = Cochrane Database Syst Rev | volume =  | issue = 1 | pages =  CD001953| year = 2007 | pmid = 17253470 | doi = 10.1002/14651858.CD001953.pub3 | editor1-last = Latte | editor1-first = G. Jenny }}</ref> Kay ipratropio aerosol kaqpi qhuña unqunayaqta pisillachinman, ichaqa mana ancha kusachu kay sinqa wichq’akuypaq. <ref>{{cite journal | author = Albalawi ZH, Othman SS, Alfaleh K | title = Intranasal ipratropium bromide for the common cold | journal = Cochrane Database of Systematic Reviews | volume =  | issue = 7 | pages =  CD008231|year = 2011 | month = July | pmid = 21735425 | doi = 10.1002/14651858.CD008231.pub2 | editor1-last = Albalawi |editor1-first = Zaina H }}</ref> Kay antihistamínicos segunda generación kaqmanta mana ancha kusasinachu kankuman.<ref>{{cite journal | author = Pratter MR | title = Cough and the common cold: ACCP evidence-based clinical practice guidelines |journal = Chest | volume = 129 | issue = 1 Suppl | pages = 72S–74S | year = 2006 | month = Jan | pmid = 16428695 | doi = 10.1378/chest.129.1_suppl.72S }}</ref>

Mana achkha yachakuy kaqrayku, mana yachakunchu sichus huk yapakuy kay ingesta yakukunapi allinllachinchus unqunayaqta utaq pisillachinchus kay respiratoria unquyta.<ref>{{cite journal | author = Guppy MP, Mickan SM, Del Mar CB, Thorning S, Rack A | title = Advising patients to increase fluid intake for treating acute respiratory infections | journal = Cochrane Database of Systematic Reviews| volume =  | issue = 2 | pages =  CD004419| year = 2011 | month = February | pmid = 21328268 | doi = 10.1002/14651858.CD004419.pub3 | editor1-last = Guppy | editor1-first = Michelle PB }}</ref> Chaymanta huk kikin willay mana kaynin tiyan kay rupha wayra q’usñichasqa churakuypaq.<ref>{{cite journal | author = Singh M, Singh M | title = Heated, humidified air for the common cold | journal = Cochrane Database of Systematic Reviews | volume =  | issue = 5 | pages =  CD001728| year = 2011 | month = May | pmid = 21563130 | doi = 10.1002/14651858.CD001728.pub4 | editor1-last = Singh| editor1-first = Meenu }}</ref> Huk yachakuy rikuchirqa kay mentoladas jawikuna qhasqupi churakuyqa yanapanman kay ch’isipi ch’ujuta, sinqa wichq’akuyta chaymanta mana puñuy atiyta allinchachinanpaq.<ref>{{cite journal | author = Paul IM, Beiler JS, King TS, Clapp ER, Vallati J, Berlin CM | title = Vapor rub, petrolatum, and no treatment for children with nocturnal cough and cold symptoms | journal = Pediatrics | volume = 126 | issue = 6 | pages = 1092–9 | year = 2010 | month = December |pmid = 21059712 | doi = 10.1542/peds.2010-1601 }}</ref>

===Antibióticos chaymanta antivirales kaqkuna===
Antibióticos kaqkunaqa mana allinchu kanchu kay infecciones virales kaqkunapaq chayraykutaq mana allinchu kanku kay ch’uju unquy virus kaqkunapaq.<ref name=CochraneAR2005>{{cite journal | author = Arroll B, Kenealy T | title = Antibiotics for the common cold and acute purulent rhinitis | journal = Cochrane Database Syst Rev | volume =  | issue = 3 | pages =  CD000247|year = 2005 | pmid = 16034850 | doi = 10.1002/14651858.CD000247.pub2 | editor1-last = Arroll | editor1-first = Bruce}}</ref> Kay efectos secundarios kaqkunarayku, waqlliy atinkuman, ichaqa, sapakuti hampikamachikunku.<ref name=CochraneAR2005/><ref>Eccles Pg.238</ref> Wakin imaraykukuna imaraykuchus antibióticos kaqkunan hampikamachikunkurayku kanku unqusqap munaynin, hampiqruna imayllatapas ruway munaynin, chaymanta kay hasallay sinchiman tukuykuna hark’ayta mayqinkunachus kay antibióticos kaqkunaman ari ñinkuman.<ref>Eccles Pg.234</ref> Mana allin antivirales millachiqkuna kay ch’uju unquy hampikuyninpi tiyanchu, ichapas wakin ñawpa yachay mask’aykuna allinninkunata rikuchirqankupas.<ref name=AFP07/><ref name="EcclesPg_b">Eccles Pg.218</ref>

===Wak aqyanapaq hampikuynin===
Ichapas achkha wak aqyanapaq hampikuynin kaptinpas, mana cientifica evidencia tiyanchu mayqinchus yanapanman kay hampikuyninta.<ref name=AFP07/> Mana achkha evidencia kanchu kay 2010 kaqpi willarinapaqhina utaq wich’unapaqhina kay miel kaqwan hampikunapaq utaq sinqa mayllakuyta.<ref>{{cite journal | author = Oduwole O, Meremikwu MM, Oyo-Ita A, Udoh EE | title = Honey for acute cough in children | journal = Cochrane Database of Systematic Reviews | volume =  | issue = 1 | pages =  CD007094| year = 2010 | month = January | pmid = 20091616 | doi = 10.1002/14651858.CD007094.pub2 | editor1-last = Oduwole | editor1-first = Olabisi }}</ref><ref>{{cite journal | author = Kassel JC, King D, Spurling GK | title = Saline nasal irrigation for acute upper respiratory tract infections | journal = Cochrane Database of Systematic Reviews | volume =  | issue = 3 | pages =  CD006821| year = 2010 | month = March | pmid = 20238351 | doi = 10.1002/14651858.CD006821.pub2 | editor1-last = King | editor1-first = David }}</ref> Wakin yachaykuna willanku zinc kaqta upyana kay 24 phani ukhupi kay unqunayaq qallarichkanmantapacha mana unqusqa runakunapi ch’uju unquy unayllayninta chaymanta sinchillayninta pisillachin.<ref name=Zinc11/> Kay achkha ukhinakuna kay yachaykunapi munachin aswan yachayta mask’anata yachanapaq imaynatachus chaymanta mayk’aqchus kay zinc allin kanman.<ref>{{cite web |url=http://www.nhs.uk/news/2011/02February/Pages/zinc-for-the-common-cold.aspx |title=Zinc for the common cold&nbsp;—Health News&nbsp;— NHS Choices |first= |last= |work=nhs.uk |year=2012 [last update] |quote=In this review, there was a high level of heterogeneity between the studies that were pooled to determine the effect of zinc on the duration of cold symptoms. This may suggest that it was inappropriate to pool them. It certainly makes this particular finding less conclusive. |accessdate=24 February 2012}}</ref> Kay vitamina C efecto kaqninqa kay ch’uju unquypi hatunpi yachakurqa mana allin tarikuywan, manataq ahinatachu kay qusqa pachakunapi, aswanta kay runakunapi pikunachus actividad fisica kaqta chiri kitikunapi ruwaq.<ref name="Hemilä2010">{{cite journal | author = Hemilä H, Chalker E, Douglas B, Hemilä H | title = Vitamin C for preventing and treating the common cold | journal = Cochrane Database of Systematic Reviews | volume =  |issue = 3 | pages =  CD000980| year = 2007 | pmid = 17636648 | doi = 10.1002/14651858.CD000980.pub3 | editor1-last = Hemilä | editor1-first = Harri }}</ref><ref name="Heimer2009">{{cite journal | author = Heiner KA, Hart AM, Martin LG, Rubio-Wallace S | title = Examining the evidence for the use of vitamin C in the prophylaxis and treatment of the common cold | journal = Journal of the American Academy of Nurse Practitioners | volume = 21 | issue = 5 | pages = 295–300 | year = 2009 | pmid = 19432914 | doi = 10.1111/j.1745-7599.2009.00409.x }}</ref> Evidencia kay echinaces kaqwan hampikuyqa mana sinchichu.<ref name=CochE06>{{cite journal | author = Linde K, Barrett B, Wölkart K, Bauer R, Melchart D | title = Echinacea for preventing and treating the common cold | journal = Cochrane Database Syst Rev |volume =  | issue = 1 | pages =  CD000530| year = 2006 | pmid = 16437427 | doi = 10.1002/14651858.CD000530.pub2 |editor1-last = Linde | editor1-first = Klaus }}</ref><ref>{{cite journal | author = Sachin A Shah, Stephen Sander, C Michael White, Mike Rinaldi, Craig I Coleman | title = Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysis | journal = The Lancet Infectious Diseases | volume = 7 | issue = 7 | pages = 473–480 |year = 2007 | pmid = 17597571 | doi = 10.1016/S1473-3099(07)70160-3 }}</ref> Kay ukhina laya Echinacea kaqwan suplementosqa ukhina kankuman allinllayninpi.<ref name=CochE06/> Mana yachakunchu sichus ajus allin kanman.<ref>{{cite journal |author = Lissiman E, Bhasale AL, Cohen M | title = Garlic for the common cold | journal = Cochrane Database Syst Rev |volume = 3 | issue =  | pages = CD006206 | year = 2012 | pmid = 22419312 | doi = 10.1002/14651858.CD006206.pub3 |editor1-last = Lissiman | editor1-first = Elizabeth }}</ref> Huk evidencialla vitamina D kaqwan mana allin kayninta tarirqachu.<ref>{{cite journal|last=Murdoch|first=David R.|title=Effect of Vitamin D<sub>3</sub> Supplementation on Upper Respiratory Tract Infections in Healthy Adults<subtitle>The VIDARIS Randomized Controlled Trial</subtitle><alt-title>Vitamin D<sub>3</sub> and Upper Respiratory Tract Infections</alt-title>|journal=JAMA: the Journal of the American Medical Association|date=3 October 2012|volume=308|issue=13|pages=1333|doi=10.1001/jama.2012.12505}}</ref>

==Pronostico nisqa==
Kay ch’uju unquy mana sinchichu chaymanta aswan achkha kaqkuna unqunayaqninmanta huk semanapi allinllapunku.<ref name=CE11/> Sichus sinchi champallaykuy tiyan chayqa ancha machu runakunapi, ancha wayna runakunapi utaq inmunosuprimidas runakunapi aswan rikukuqpi rikukun.<ref name=E1/> Secundarias infecciones bacteriales ruwakunman kay sinusitis kaqhina, faringitis kaqhina utaq otitis aguda kaqhina.<ref>Eccles Pg.76</ref> Tantiyakun 8% casosmanta sinusitis ruwakun, otitis kaqtaq ruwakun 30% casosmanta.<ref name="EcclesPg_a">Eccles Pg.90</ref>

==Epidemiologia nisqa==
Kay ch’uju unquyqa aswan riqsisqa runa unquy kan<ref name=E1>Eccles Pg. 1</ref> chaymanta tukuy ayllukunaman pachamanta hap’in.<ref name=Text2007/> Machu runakunaqa watapi iskaymanta phichqa infecciones kaqtahina hap’in<ref name=CE11>{{cite journal |author = Arroll B | title = Common cold | journal = Clinical evidence | volume = 2011 | issue = 3 | pages =  | year = 2011 | month = March | pmid = 21406124 | doi =  }}</ref><ref name=Eccles2005/> wawakunataq watapi suqtamanta chunka ch’uju unquykunatahina hap’inkuman (yachaywasipi kaqkunari watapi chunka iskayniyuq ch’uju unquyhinata hap’inkuman).<ref name=AFP07>{{cite journal | author = Simasek M, Blandino DA | title = Treatment of the common cold | journal = American Family Physician | volume = 75 | issue = 4 | pages = 515–20 | year = 2007 | pmid = 17323712 | doi =  | url = http://www.aafp.org/afp/20070215/515.html }}</ref> Kay sintomaticas chimpakuykuna yupayninqa machu runakunapi yapakun kay mana unqunapaq sistema mawq’allayninrayku.<ref name=E78>Eccles Pg. 78</ref>

==Rikhurimuynin==
Kay ch’uju unquy causanpas riqsisqa kaptinpas kay 1950s kaqpi, kay unquyqa runakunawan kachkarqa ñawpamantapacha.<ref>Eccles Pg. 3</ref> Unqunayaqnin chaymanta hampikuynin allinta willakun kay papiro egipcio Ebers kaqpi, aswan riqsisqa mawq’a hampiq p’anqa, qillqasqa ñawpata kay siglo 16 AC kaqpi.<ref>Eccles Pg.6</ref> Ingles kaqpi sutiqa, “common cold” kay siglo 16 kaqpi apaykachakurqa, kay rich’akuyrayku unqunayaqninpi kay chiriman rikuchikuy imawan.<ref>{{cite web | publisher=Online Etymology Dictionary | url=http://www.etymonline.com/index.php?term=cold |title=Cold | accessdate=12 January 2008 }}</ref>

Reino Unido kaqpi, kay Medical Research Council paqarichirqa kay Common Cold Unit 1946 kaqpi chaymanta chaypi karqa maypichus kay rinovirus tarikurqa kay 1956 kaqpi.<ref>Eccles Pg.20</ref> Kay 70 watakunapi, kay CCU kaq rikuchirqa kay interferones kaqwan hampikuyninqa kay thapachakuy pachapi kay rinovirus chimpachiy  kaqmanta hark’an kay unquymanta,<ref name="pmid2438740">{{cite journal | author = Tyrrell DA | title = Interferons and their clinical value | journal = Rev. Infect. Dis. | volume = 9 | issue = 2 | pages = 243–9 | year = 1987 | pmid = 2438740 | doi = 10.1093/clinids/9.2.243 }}</ref> ichaqa mana hasa hampikuyninta ruway atirqachu. Kay 1989 kaqpi unidad kaqta wichq’arqanku, iskay watamanta kay yachay mask’ana hunt’achikuptin kay zinc kaqmanta gluconato tabletas kaqmanta hark’anapaq kay ch’uju unquykunata kay rinovirus kaqrayku, kay huk allin hampikuyninlla kay unidad thaskiyninpi.<ref>{{cite journal | author = Al-Nakib W | title = Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges | journal = J Antimicrob Chemother. | volume = 20 | issue = 6 | pages = 893–901 | year = 1987 |month = December | pmid = 3440773 | doi = 10.1093/jac/20.6.893 | last2 = Higgins | first2 = P.G. | last3 = Barrow |first3 = I. | last4 = Batstone | first4 = G. | last5 = Tyrrell | first5 = D.A.J. }}</ref>

==Impacto economico nisqa==
[[Image:The Cost Of The Common Cold & Influenza.jpg|thumb|Huk británico letrero kay Segunda Guerra Mundial kaqmanta mayqinchus willan ch’uju unquymanta costonta<ref>{{cite web |title=The Cost of the Common Cold and Influenza |work=Imperial War Museum: Posters of Conflict |publisher=vads|url=http://vads.bath.ac.uk/flarge.php?uid=33443&sos=0}}</ref>]]
Aswan achkha pacha k’uchukunapi, mana allinta yachakunchu kay ch’uju unquy impacto kaqnin.<ref name="EcclesPg_a" /> Kay Estados Unidos kaqpi, kay ch’uju unquy 75-100 junu jampiq runa tapuykunaman apan sapa wata, huk 7700 junu dólares watapi tantiyasqa chaninniyuq. Estadounidenses kaqkunaqa 2900 hunu dolaresta chikchanku kay pillamanpas ranqhay hampikunapi chaymanta 400 hunutataq kamachisqa hampikunapi kay unqunayaq allinllaypaq.<ref name=Frend03>{{cite journal | author = Fendrick AM, Monto AS, Nightengale B, Sarnes M | title = The economic burden of non-influenza-related viral respiratory tract infection in the United States| journal = Arch. Intern. Med. | volume = 163 | issue = 4 | pages = 487–94 | year = 2003 | pmid = 12588210 | doi = 10.1001/archinte.163.4.487 }}</ref> Aswan huk tercio runakunamanta huk jampiq runaman riqkuna huk antibióticos kamachiyta quchikurqanku, kaytaq efectosniyuq kay antibiótica k’ullukuypi.<ref name=Frend03/> Tantiyakun estadounidenses wawakuna 22-189 hunu yachaywasi p’unchawkunata sapa wata saqipunku kay ch’uju unquyrayku. Ahinatataq, tatakuna 126 hunu llamk’ana p’unchawkunata saqipunku ch’ujumanta unqusqa wawankuta qhawanankupaq. Kay 150 hunu saqipusqa llamk’ana p’unchawkunaman yapakuptin kay ch’ujumanta unqusqa llamk’aqkunarayku, kay total económico impacto kaqqa ch’uju unquymanta atipan kay 20 hunu dolaresta sapa wata.<ref name="NIAID2006"/><ref name=Frend03/> Kay ch’uju unquyqa 40% saqipusqa llamk’ana kaqmanta huchachakun kay Estados Unidos kaqpi.<ref>{{cite journal | author = Kirkpatrick GL | title = The common cold| journal = Prim. Care | volume = 23 | issue = 4 | pages = 657–75 | year = 1996 | month = December | pmid = 8890137 |doi = 10.1016/S0095-4543(05)70355-9 }}</ref>

==Yachana mask’ay==
Achkha antivirales yanakurqanku, ichaqa 2009 kaqkama ni huk allin karqachu kay ch’uju unquypaq.<ref name="EcclesPg_b" /> kay antiviral pleconaril millachiq yanakuchkan mayqinchus allin kanman kay picornaviruspaq, kay droga BTA-798 chaymantapas.<ref name=E226>Eccles Pg.226</ref> Kay oral churakuynin kay pleconaril kaqmanta ch’ampa hark’akuy rikuchin, chayraykutaq kay aerosol kaqpi kayninta yachaqakuchkan.<ref name=E226/>

Yachay mask’aqkuna kay Universidad Maryland, College Par chaymanta kay Universidad Wisconsin-Madison kaqmanta kaqkunaqa kay tukuy riqsisqa virusmanta mayqinkunachus ch’uju unquyta hap’ichiq genoma kaqninta tarirqanku.<ref name="CTgov">{{cite news| url =http://www.cnn.com/2009/HEALTH/02/12/cold.genome/| title = Genetic map of cold virus a step toward cure, scientists say| date = February 12, 2009 | accessdate = 28 April 2009| publisher = CNN| author = Val Willingham}}</ref>
{{-}}

==Referencias==
{{Reflist|colwidth=35em}}

==Bibliografía ==
{{refbegin}}
* {{cite book|last=Ronald Eccles|first=Olaf Weber (eds)|title=Common cold|year=2009|publisher=Birkhäuser|location=Basel|isbn=978-3-7643-9894-1 }}
{{refend}}

==Enlaces externos==
{{Commons category|Common cold}}
* {{dmoz|Health/Conditions_and_Diseases/Respiratory_Disorders/Common_Cold/}}

{{Viral diseases}}
{{Respiratory pathology}}
{{Common Cold}}

[[Katiguriya:Unquy]]

[[Category:Acute upper respiratory infections]]
[[Category:Infectious diseases]]
[[Category:Inflammations]]
[[Category:Viral diseases]]
[[Category:Viruses]]