CRISPR
CRISPR (huk huch'uchasqa clustered regularly interspaced short palindromic repeatkuna) nisqaqa huk ADN secuenciakunap ayllun, ñawpaq-kariyuta kawsaqkunap genomankunapi tarikuq, ahinataq añaki, ñawpa añaki.[1] Kay secuenciakunaqa bacteriófagos nisqapa ADN fragmentos nisqamanta hurqusqam, chaykunam ñawpaqta ñawpaq-kariyuta nisqaman infectasqa karqa. Chaykunataqa llamk’achinku ADNta riqsinankupaq, chinkachinankupaq ima, chayman rikch’akuq bacteriófagos nisqamanta, qhipa infecciones kaptin. Kayrayku kay secuenciakuna huk clave ruwayta ruwanku kay antiviral (kayqa antifago) sistema de defensa kaqpi kay procariotas kaqmanta chanta huk forma kay inmunidad adquirida kaqmanta qunku.[1][2] [3] [4] CRISPR tarikun yaqa 50% kaqpi secuenciadokuna genomas bacterianos kaqpi chanta yaqa 90% kaqpi kay arqueos secuenciadokuna kaqpi.[5]
Pukyukuna[llamk'apuy | pukyuta llamk'apuy]
- ↑ 1,0 1,1 "The roles of CRISPR-Cas systems in adaptive immunity and beyond". Current Opinion in Immunology 32: 36–41. 2015. Error: Bad DOI specified. PMID 25574773.
- ↑ "What is CRISPR/Cas9?". Archives of Disease in Childhood: Education and Practice Edition 101 (4): 213–215. August 2016. Error: Bad DOI specified. PMID 27059283.
- ↑ "CRISPR provides acquired resistance against viruses in prokaryotes". Science 315 (5819): 1709–1712. March 2007. Error: Bad DOI specified. PMID 17379808. Bibcode 2007Sci...315.1709B. Plantilla:Registration required
- ↑ "CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA". Science 322 (5909): 1843–1845. December 2008. Error: Bad DOI specified. PMID 19095942. Bibcode 2008Sci...322.1843M.
- ↑ "The Biology of CRISPR-Cas: Backward and Forward". Cell 172 (6): 1239–1259. March 2018. Error: Bad DOI specified. PMID 29522745.
- ↑ "CRISPR/Cas, the immune system of bacteria and archaea". Science 327 (5962): 167–170. January 2010. Error: Bad DOI specified. PMID 20056882. Bibcode 2010Sci...327..167H.